Disulfide Bridges in Tropomyosin

Disulfide bridges in human complement component C3b.

The disulfide bridges of human complement component C3b, derived from C3 by removal of the 77-residue C3a, have been determined. The 10 bridges are Cys537-Cys794, Cys605-Cys640, Cys851-Cys1491, Cys1079-Cys1136, Cys1336-Cys1467, Cys1367-Cys1436, Cys1484-Cys1489, Cys1496-Cys1568, Cys1515-Cys1639, and Cys1615-Cys1624. Including the 3 bridges in C3a (Cys670-Cys698, Cys672-Cys705, and Cys685-Cys706)...

Reductive cleavage of disulfide bridges in ribonuclease.

Immunoglobulin disulfide bridges: theme and variations.

DBDB : a Disulfide Bridge DataBase for the predictive analysis of cysteine residues involved in disulfide bridges

We present a database of structured, verified and useful information about cysteine residues involved in disulfide bridges. The database has been filled with proteins of a subset of the PDB database called select 25. A rough analysis of the proteins contained in the database shows that it is possible to identify cysteine residues which are involved or not in a disulfide bond from the amino acid...

Converting disulfide bridges in native peptides to stable methylene thioacetals.

Disulfide bridges play a crucial role in defining and rigidifying the three-dimensional structure of peptides. However, disulfides are inherently unstable in reducing environments. Consequently, the development of strategies aiming to circumvent these deficiencies - ideally with little structural disturbance - are highly sought after. Herein, we report a simple protocol converting the disulfide...